| Risk Factors | Intervention Strategies |
| Physical: Examples | |
| Familial tendency for malocclusion | Early intervention |
| Conditions associated with malocclusion (e.g., cleft lip/palate) | Early intervention |
| Variations in development (e.g., tooth eruption delays and malpositioned teeth) | Early intervention |
| Congenital absence of teeth | Early intervention |
| Mouthbreathing | Management of mouthbreathing |
| Muscular imbalances | Early therapy |
| Behavioral: Examples | |
| Non nutritive sucking habits in children ages 4 and above | Elimination of habit |
| Disease or Treatment Related: Examples | |
| Loss of space owing to dental caries | Early intervention for dental caries |
| Skeletal growth disorders (e.g., renal disease) | Dental intervention as a part of medical care |
| Acquired problem from systemic condition or its therapy | Dental intervention as a part of medical care |
| Musculoskeletal conditions (e.g., cerebral palsy) | Dental intervention as a part of medical care |
| Injury | Use of age-appropriate safety measures (e.g., car seats, booster seats, seat belts, stair gates, mouth guards) and treatment of injury |